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KMID : 1007520080170020425
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Food Science and Biotechnology
2008 Volume.17 No. 2 p.425 ~ p.429
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Inhibition of Lipid Accumulation in 3T3-L1 Adipocytes by Extract of Chokong, Rhynchosia nolubilis Seeds Pickled in Vinegar
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Shin Jee-Young
Park La-Young
Oh Young-Sook
Lee Shin-Ho
Youn Kwang-Sup
Kim Seok-Joong
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Abstract
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The anti-obesity effect of chokong, Rhynchosia nolubilis seeds pickled in vinegars for 2 weeks at 4℃, was investigated. During the differentiation of 3T3-L1 adipocytes, the addition of ethanolic extracts of chokongs lowered the cellular triglyceride content by 8.1-9.0%, and glucose content by 12.2-27.6%, depending on the kinds of vinegar used. The activity of glycerol-3-phosphate dehydrogenase also decreased up to 56.0-59.3% by supplying those extracts. In addition, vinegars were superior to acetic acid, citric acid, and hydrochloric acid solutions, and distilled water in anti-obesity of the pickled seeds.
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KEYWORD
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Rhynchosia nolubilis seed, vinegar, 3T3-L1 cell, triglyceride, glycerol-3-phosphate dehydrogenase
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